While Fallout's raiders cannot be compared to Super Mario's Goombas in terms of physical interaction, their roles are somewhat similar.
Given the undeniable presence of raiders in the Fallout universe, Fallout 5 could introduce a completely new version of these familiar enemies, providing a fresh experience for fans. However, even long-running aspects of the series can benefit from innovation from time to time. It is difficult to imagine a Fallout game without raiders, as they have consistently appeared at various levels throughout the series.
One significant change that could be made to Fallout 5's raiders is incorporating ideas from Fallout 76.